V. CONTRACTION
A. Neuromuscular Junction = Motor end-plate
1. Motor neuron
2. Neurotransmitter (Acetylcholine)
3. Motor unit
B. Excitation/contraction Coupling=Sliding Filament Theory
1. T Tubules
2. Calcium
Short lived release
3. Myosin
ATP binding site
Actin binding site
4. Troponin and tropomyosin move
5. Myosin
Attaches actin
Moves towards sarcomere center = Power Stroke
C. Regulation; Calcium
D. ATP sources
1. Skeletal muscle
2. Creatine phosphate
3. Aerobic metabolism
4. Anaerobic metabolism (lactic acid)
5. Muscle fatigue
E. Oxygen and Glycogen debt